NCBI Description of CELF1
|Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene. Alternative splicing results in multiple transcript variants encoding different isoforms.|
Community Annotation of CELF1 Add / Edit CELF1: Annotations
No community annotations yet for CELF1.
• "Mouse over" a mutation to see details.
Click on a tumor type to see its full list of significant genes.