CDX1 Back

caudal type homeobox 1

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NCBI Description of CDX1

This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded DNA-binding protein regulates intestine-specific gene expression and enterocyte differentiation. It has been shown to induce expression of the intestinal alkaline phosphatase gene, and inhibit beta-catenin/T-cell factor transcriptional activity.

Community Annotation of CDX1 Add / Edit CDX1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CDX1 is highly significantly mutated in
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CDX1 is significantly mutated in
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CDX1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for CDX1