CDKL1 Back

cyclin-dependent kinase-like 1 (CDC2-related kinase)

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NCBI Description of CDKL1

This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the nucleus. Alternative splice variants encoding different protein isoforms have been described, but their full-length nature has not been determined.

Community Annotation of CDKL1 Add / Edit CDKL1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CDKL1 is highly significantly mutated in
(none)
CDKL1 is significantly mutated in
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CDKL1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for CDKL1