CDK5RAP1 Back

CDK5 regulatory subunit associated protein 1

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NCBI Description of CDK5RAP1
Neuronal CDC2-like kinase, which is involved in the regulation of neuronal differentiation, is composed of a catalytic subunit, CDK5, and an activating subunit, p25NCK5A. The protein encoded by this gene binds to p25NCK5A and therefore may be involved in neuronal differentiation. Multiple transcript variants exist for this gene, but the full-length natures of only two have been determined.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CDK5RAP1 is highly significantly mutated in
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CDK5RAP1 is significantly mutated in
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CDK5RAP1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CDK5RAP1