CDK5R2 Back

cyclin-dependent kinase 5, regulatory subunit 2 (p39)

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NCBI Description of CDK5R2
The protein encoded by this gene is a neuron-specific activator of CDK5 kinase. It associates with CDK5 to form an active kinase. This protein and neuron-specific CDK5 activator CDK5R1/p39NCK5A both share limited similarity to cyclins, and thus may define a distinct family of cyclin-dependent kinase activating proteins. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.

Community Annotation of CDK5R2 Add / Edit CDK5R2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CDK5R2 is highly significantly mutated in
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CDK5R2 is significantly mutated in
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CDK5R2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CDK5R2