CDK19 Back

cyclin-dependent kinase 19

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NCBI Description of CDK19
This gene encodes a protein that is one of the components of the Mediator coactivator complex. The Mediator complex is a multiprotein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex.

Community Annotation of CDK19 Add / Edit CDK19: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CDK19 is highly significantly mutated in
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CDK19 is significantly mutated in
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CDK19 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CDK19