CDK16 Back

cyclin-dependent kinase 16

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NCBI Description of CDK16
The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It may play a role in signal transduction cascades in terminally differentiated cells; in exocytosis; and in transport of secretory cargo from the endoplasmic reticulum. This gene is thought to escape X inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.

Community Annotation of CDK16 Add / Edit CDK16: Annotations

No community annotations yet for CDK16.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CDK16 is highly significantly mutated in
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CDK16 is significantly mutated in
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CDK16 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CDK16