CDH23 Back

cadherin-like 23

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of CDH23
This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Alternative splice variants encoding different isoforms have been described.

Community Annotation of CDH23 Add / Edit CDH23: Annotations

No community annotations yet for CDH23.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CDH23 is highly significantly mutated in
(none)
CDH23 is significantly mutated in
(none)
CDH23 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CDH23