CDCP1 Back

CUB domain containing protein 1

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NCBI Description of CDCP1
The protein encoded by this gene is a transmembrane protein containing three extracellular CUB domains. This protein is found to be overexpressed in colon and lung cancers. Its expression level is correlated with the metastatic ability of carcinoma cells. This protein is located on the cell surface. It has been shown to be tyrosine phosphorylated in a cancer cell line. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Community Annotation of CDCP1 Add / Edit CDCP1: Annotations

No community annotations yet for CDCP1.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CDCP1 is highly significantly mutated in
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CDCP1 is significantly mutated in
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CDCP1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CDCP1