CDCA7 Back

cell division cycle associated 7

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NCBI Description of CDCA7
This gene was identified as a c-Myc responsive gene, and behaves as a direct c-Myc target gene. Overexpression of this gene is found to enhance the transformation of lymphoblastoid cells, and it complements a transformation-defective Myc Box II mutant, suggesting its involvement in c-Myc-mediated cell transformation. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.

Community Annotation of CDCA7 Add / Edit CDCA7: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CDCA7 is highly significantly mutated in
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CDCA7 is significantly mutated in
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CDCA7 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CDCA7