CDC7 Back

cell division cycle 7 homolog (S. cerevisiae)

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NCBI Description of CDC7
This gene encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple alternatively spliced transcript variants that encode the same protein have been detected.

Community Annotation of CDC7 Add / Edit CDC7: Annotations

No community annotations yet for CDC7.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CDC7 is highly significantly mutated in
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CDC7 is significantly mutated in
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CDC7 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CDC7