CDC5L Back

CDC5 cell division cycle 5-like (S. pombe)

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NCBI Description of CDC5L

The protein encoded by this gene shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. This protein has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

Community Annotation of CDC5L Add / Edit CDC5L: Annotations

No community annotations yet for CDC5L.
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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


CDC5L is highly significantly mutated in
CDC5L is significantly mutated in
CDC5L is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for CDC5L