CDC42 binding protein kinase beta (DMPK-like)

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NCBI Description of CDC42BPB

This gene encodes a member of the serine/threonine protein kinase family. The encoded protein contains a Cdc42/Rac-binding p21 binding domain resembling that of PAK kinase. The kinase domain of this protein is most closely related to that of myotonic dystrophy kinase-related ROK. Studies of the similar gene in rat suggested that this kinase may act as a downstream effector of Cdc42 in cytoskeletal reorganization.

Community Annotation of CDC42BPB Add / Edit CDC42BPB: Annotations

No community annotations yet for CDC42BPB.
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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


CDC42BPB is highly significantly mutated in
CDC42BPB is significantly mutated in
CDC42BPB is near significance in

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Data details

Mutation list for CDC42BPB