CDC40 Back

cell division cycle 40 homolog (S. cerevisiae)

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NCBI Description of CDC40
Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression.

Community Annotation of CDC40 Add / Edit CDC40: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CDC40 is highly significantly mutated in
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CDC40 is significantly mutated in
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CDC40 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CDC40