CDC37 Back

cell division cycle 37 homolog (S. cerevisiae)

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NCBI Description of CDC37
The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.

Community Annotation of CDC37 Add / Edit CDC37: Annotations

No community annotations yet for CDC37.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CDC37 is highly significantly mutated in
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CDC37 is significantly mutated in
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CDC37 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CDC37