CDC25C Back

cell division cycle 25 homolog C (S. pombe)

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NCBI Description of CDC25C
This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.

Community Annotation of CDC25C Add / Edit CDC25C: Annotations

No community annotations yet for CDC25C.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CDC25C is highly significantly mutated in
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CDC25C is significantly mutated in
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CDC25C is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CDC25C