CDC16 Back

cell division cycle 16 homolog (S. cerevisiae)

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NCBI Description of CDC16
This gene encodes a component protein of the APC complex, which is composed of eight proteins and functions as a protein ubiquitin ligase. The APC complex is a cyclin degradation system that governs exit from mitosis. Each component protein of the APC complex is highly conserved among eukaryotic organisms. This protein and two other APC complex proteins, CDC23 and CDC27, contain a tetratricopeptide repeat (TPR), a protein domain that may be involved in protein-protein interaction. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Community Annotation of CDC16 Add / Edit CDC16: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CDC16 is highly significantly mutated in
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CDC16 is significantly mutated in
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CDC16 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CDC16