CD3G Back

CD3g molecule, gamma (CD3-TCR complex)

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of CD3G

The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency.

Community Annotation of CD3G Add / Edit CD3G: Annotations

No community annotations yet for CD3G.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CD3G is highly significantly mutated in
(none)
CD3G is significantly mutated in
(none)
CD3G is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for CD3G