CD226 Back

CD226 molecule

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of CD226

This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation.

Community Annotation of CD226 Add / Edit CD226: Annotations

No community annotations yet for CD226.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CD226 is highly significantly mutated in
(none)
CD226 is significantly mutated in
(none)
CD226 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for CD226