CD200 Back

CD200 molecule

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NCBI Description of CD200

The protein encoded by this gene is a type-1 membrane glycoprotein, which contains two immunoglobulin domains, and thus belongs to the immunoglobulin superfamily. Studies of the related genes in mouse and rat suggest that this gene may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene.

Community Annotation of CD200 Add / Edit CD200: Annotations

No community annotations yet for CD200.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CD200 is highly significantly mutated in
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CD200 is significantly mutated in
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CD200 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for CD200