CD180 Back

CD180 molecule

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of CD180
CD180 is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. The extracellular LRR is associated with a molecule called MD-1 and form the cell surface receptor complex, RP105/MD-1. It belongs to the family of pathogen receptors, Toll-like receptors (TLR). RP105/MD1, by working in concert with TLR4, controls B cell recognition and signaling of lipopolysaccharide (LPS), a membrane constituent of Gram-negative bacteria.

Community Annotation of CD180 Add / Edit CD180: Annotations

No community annotations yet for CD180.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CD180 is highly significantly mutated in
(none)
CD180 is significantly mutated in
(none)
CD180 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CD180