CD151 Back

CD151 molecule (Raph blood group)

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of CD151
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene.

Community Annotation of CD151 Add / Edit CD151: Annotations

No community annotations yet for CD151.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CD151 is highly significantly mutated in
(none)
CD151 is significantly mutated in
(none)
CD151 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CD151