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CD14 molecule

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NCBI Description of CD14

The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide. Alternative splicing results in multiple transcript variants encoding the same protein.

Community Annotation of CD14 Add / Edit CD14: Annotations

No community annotations yet for CD14.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CD14 is highly significantly mutated in
(none)
CD14 is significantly mutated in
(none)
CD14 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for CD14