CCT7 Back

chaperonin containing TCP1, subunit 7 (eta)

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NCBI Description of CCT7
This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 6.

Community Annotation of CCT7 Add / Edit CCT7: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CCT7 is highly significantly mutated in
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CCT7 is significantly mutated in
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CCT7 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CCT7