CCT6A Back

chaperonin containing TCP1, subunit 6A (zeta 1)

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NCBI Description of CCT6A
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, several pseudogenes of this gene have been located.

Community Annotation of CCT6A Add / Edit CCT6A: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CCT6A is highly significantly mutated in
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CCT6A is significantly mutated in
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CCT6A is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CCT6A