CCT2 Back

chaperonin containing TCP1, subunit 2 (beta)

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NCBI Description of CCT2

The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Two transcript variants encoding different isoforms have been found for this gene.

Community Annotation of CCT2 Add / Edit CCT2: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


CCT2 is highly significantly mutated in
CCT2 is significantly mutated in
CCT2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for CCT2