CCNL2 Back

cyclin L2

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NCBI Description of CCNL2
The protein encoded by this gene belongs to the cyclin family. Through its interaction with several proteins, such as RNA polymerase II, splicing factors, and cyclin-dependent kinases, this protein functions as a regulator of the pre-mRNA splicing process, as well as in inducing apoptosis by modulating the expression of apoptotic and antiapoptotic proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Community Annotation of CCNL2 Add / Edit CCNL2: Annotations

No community annotations yet for CCNL2.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CCNL2 is highly significantly mutated in
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CCNL2 is significantly mutated in
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CCNL2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CCNL2