CCL3 Back

chemokine (C-C motif) ligand 3

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of CCL3

This locus represents a small inducible cytokine. The encoded protein, also known as macrophage inflammatory protein 1 alpha, plays a role in inflammatory responses through binding to the receptors CCR1, CCR4 and CCR5. Polymorphisms at this locus may be associated with both resistance and susceptibility to infection by human immunodeficiency virus type 1.

Community Annotation of CCL3 Add / Edit CCL3: Annotations

No community annotations yet for CCL3.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CCL3 is highly significantly mutated in
(none)
CCL3 is significantly mutated in
(none)
CCL3 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for CCL3