CCL28 Back

chemokine (C-C motif) ligand 28

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NCBI Description of CCL28
This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for resting CD4 or CD8 T cells and eosinophils. The product of this gene binds to chemokine receptors CCR3 and CCR10. This chemokine may play a role in the physiology of extracutaneous epithelial tissues, including diverse mucosal organs.

Community Annotation of CCL28 Add / Edit CCL28: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CCL28 is highly significantly mutated in
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CCL28 is significantly mutated in
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CCL28 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CCL28