CCL27 Back

chemokine (C-C motif) ligand 27

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of CCL27

This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation.

Community Annotation of CCL27 Add / Edit CCL27: Annotations

No community annotations yet for CCL27.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


CCL27 is highly significantly mutated in
CCL27 is significantly mutated in
CCL27 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for CCL27