CCL19 Back

chemokine (C-C motif) ligand 19

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NCBI Description of CCL19

This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene may play a role in normal lymphocyte recirculation and homing. It also plays an important role in trafficking of T cells in thymus, and in T cell and B cell migration to secondary lymphoid organs. It specifically binds to chemokine receptor CCR7.

Community Annotation of CCL19 Add / Edit CCL19: Annotations

No community annotations yet for CCL19.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CCL19 is highly significantly mutated in
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CCL19 is significantly mutated in
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CCL19 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for CCL19