CCL11 Back

chemokine (C-C motif) ligand 11

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NCBI Description of CCL11
This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil specific chemokine assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections.

Community Annotation of CCL11 Add / Edit CCL11: Annotations

No community annotations yet for CCL11.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CCL11 is highly significantly mutated in
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CCL11 is significantly mutated in
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CCL11 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CCL11