CCL1 Back

chemokine (C-C motif) ligand 1

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NCBI Description of CCL1
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine receptor CCR8.

Community Annotation of CCL1 Add / Edit CCL1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CCL1 is highly significantly mutated in
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CCL1 is significantly mutated in
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CCL1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CCL1