CBR3 Back

carbonyl reductase 3

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NCBI Description of CBR3

Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1.

Community Annotation of CBR3 Add / Edit CBR3: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CBR3 is highly significantly mutated in
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CBR3 is significantly mutated in
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CBR3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for CBR3