CASKIN2 Back

CASK interacting protein 2

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NCBI Description of CASKIN2
This gene encodes a large protein that contains six ankyrin repeats, as well as a Src homology 3 (SH3) domain and two sterile alpha motif (SAM) domains, which may be involved in protein-protein interactions. The C-terminal portion of this protein is proline-rich and contains a conserved region. A related protein interacts with calcium/calmodulin-dependent serine protein kinase (CASK). Alternative splicing results in multiple transcript variants.

Community Annotation of CASKIN2 Add / Edit CASKIN2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CASKIN2 is highly significantly mutated in
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CASKIN2 is significantly mutated in
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CASKIN2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CASKIN2