CASC4 Back

cancer susceptibility candidate 4

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of CASC4
The increased expression level of this gene is associated with HER-2/neu proto-oncogene overexpression. Amplification and resulting overexpression of this proto-oncogene are found in approximately 30% of human breast and 20% of human ovarian cancers. Alternatively spliced variants encoding different isoforms have been identified for this gene.

Community Annotation of CASC4 Add / Edit CASC4: Annotations

No community annotations yet for CASC4.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CASC4 is highly significantly mutated in
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CASC4 is significantly mutated in
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CASC4 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CASC4