CARTPT Back

CART prepropeptide

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NCBI Description of CARTPT
This gene encodes a secreted protein which is processed by prohormone/proprotein convertases to produce smaller, biologically active peptides. Expression of the transcript for this gene is regulated by certain drugs such as cocaine, and the encoded protein is thought to be involved in the regulation of appetite and stress. Mutations in this gene are associated with susceptibility to obesity.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CARTPT is highly significantly mutated in
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CARTPT is significantly mutated in
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CARTPT is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CARTPT