capping protein (actin filament) muscle Z-line, alpha 2

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NCBI Description of CAPZA2

The protein encoded by this gene is a member of the F-actin capping protein alpha subunit family. It is the alpha subunit of the barbed-end actin binding protein Cap Z. By capping the barbed end of actin filaments, Cap Z regulates the growth of the actin filaments at the barbed end.

Community Annotation of CAPZA2 Add / Edit CAPZA2: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


CAPZA2 is highly significantly mutated in
CAPZA2 is significantly mutated in
CAPZA2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for CAPZA2