CAPN13 Back

calpain 13

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NCBI Description of CAPN13
The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes a member of the calpain large subunit family.

Community Annotation of CAPN13 Add / Edit CAPN13: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CAPN13 is highly significantly mutated in
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CAPN13 is significantly mutated in
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CAPN13 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CAPN13