CAMK2N2 Back

calcium/calmodulin-dependent protein kinase II inhibitor 2

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of CAMK2N2
This gene encodes a protein that is highly similar to the rat CaM-KII inhibitory protein, an inhibitor of calcium/calmodulin-dependent protein kinase II (CAMKII). CAMKII regulates numerous physiological functions, including neuronal synaptic plasticity through the phosphorylation of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-type glutamate (AMPA) receptors. Studies of the similar protein in rat suggest that this protein may function as a negative regulator of CaM-KII and may act to inhibit the phosphorylation of AMPA receptors.

Community Annotation of CAMK2N2 Add / Edit CAMK2N2: Annotations

No community annotations yet for CAMK2N2.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CAMK2N2 is highly significantly mutated in
(none)
CAMK2N2 is significantly mutated in
(none)
CAMK2N2 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.