CAMK2G Back

calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma

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NCBI Description of CAMK2G
The product of this gene is one of the four subunits of an enzyme which belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a gamma chain. Many alternatively spliced transcripts encoding different isoforms have been described but the full-length nature of all the variants has not been determined.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CAMK2G is highly significantly mutated in
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CAMK2G is significantly mutated in
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CAMK2G is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CAMK2G