CAMK2D Back

calcium/calmodulin-dependent protein kinase (CaM kinase) II delta

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NCBI Description of CAMK2D
The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a delta chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CAMK2D is highly significantly mutated in
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CAMK2D is significantly mutated in
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CAMK2D is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CAMK2D