CALCOCO2 Back

calcium binding and coiled-coil domain 2

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NCBI Description of CALCOCO2

This gene encodes a coiled-coil domain-containing protein. The encoded protein functions as a receptor for ubiquitin-coated bacteria and plays an important role in innate immunity by mediating macroautophagy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Community Annotation of CALCOCO2 Add / Edit CALCOCO2: Annotations

No community annotations yet for CALCOCO2.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CALCOCO2 is highly significantly mutated in
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CALCOCO2 is significantly mutated in
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CALCOCO2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for CALCOCO2