Ca2+-dependent activator protein for secretion 2

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NCBI Description of CADPS2

This gene encodes a member of the calcium-dependent activator of secretion (CAPS) protein family, which are calcium binding proteins that regulate the exocytosis of synaptic and dense-core vesicles in neurons and neuroendocrine cells. Mutations in this gene may contribute to autism susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene.

Community Annotation of CADPS2 Add / Edit CADPS2: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


CADPS2 is highly significantly mutated in
CADPS2 is significantly mutated in
CADPS2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for CADPS2