CADM2 Back

cell adhesion molecule 2

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NCBI Description of CADM2
This gene encodes a member of the synaptic cell adhesion molecule 1 (SynCAM) family which belongs to the immunoglobulin (Ig) superfamily. The encoded protein has three Ig-like domains and a cytosolic protein 4.1 binding site near the C-terminus. Proteins belonging to the protein 4.1 family crosslink spectrin and interact with other cytoskeletal proteins. Multiple transcript variants encoding different isoforms have been found for this gene.

Community Annotation of CADM2 Add / Edit CADM2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CADM2 is highly significantly mutated in
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CADM2 is significantly mutated in
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CADM2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CADM2