CACNG5 Back

calcium channel, voltage-dependent, gamma subunit 5

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NCBI Description of CACNG5
The protein encoded by this gene is a type II transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type I TARP and a calcium channel gamma subunit. This gene is a susceptibility locus for schizophrenia and bipolar disorder.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CACNG5 is highly significantly mutated in
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CACNG5 is significantly mutated in
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CACNG5 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CACNG5