NCBI Description of CACNA2D2
|This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized.|
Community Annotation of CACNA2D2 Add / Edit CACNA2D2: Annotations
No community annotations yet for CACNA2D2.
• "Mouse over" a mutation to see details.
Click on a tumor type to see its full list of significant genes.