CACNA1I Back

calcium channel, voltage-dependent, T type, alpha 1I subunit

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NCBI Description of CACNA1I
This gene encodes the pore-forming alpha subunit of a voltage gated calcium channel. The encoded protein is a member of a subfamily of calcium channels referred to as is a low voltage-activated, T-type, calcium channel. The channel encoded by this protein is characterized by a slower activation and inactivation compared to other T-type calcium channels. This protein may be involved in calcium signaling in neurons. Alternate splicing results in multiple transcript variants.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CACNA1I is highly significantly mutated in
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CACNA1I is significantly mutated in
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CACNA1I is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CACNA1I