NCBI Description of CABIN1
|Calcineurin plays an important role in the T-cell receptor-mediated signal transduction pathway. The protein encoded by this gene binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction. The encoded protein is found in the nucleus and contains a leucine zipper domain as well as several PEST motifs, sequences which confer targeted degradation to those proteins which contain them. Alternative splicing results in multiple transcript variants encoding two different isoforms.|
Community Annotation of CABIN1 Add / Edit CABIN1: Annotations
No community annotations yet for CABIN1.
• "Mouse over" a mutation to see details.
Click on a tumor type to see its full list of significant genes.