CA7 Back

carbonic anhydrase VII

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of CA7
Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. The cytosolic protein encoded by this gene is predominantly expressed in the salivary glands. Alternative splicing in the coding region results in multiple transcript variants encoding different isoforms.

Community Annotation of CA7 Add / Edit CA7: Annotations

No community annotations yet for CA7.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CA7 is highly significantly mutated in
(none)
CA7 is significantly mutated in
(none)
CA7 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CA7